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Why do people having head injury almost alway developed fever?
” In ADS, altered autonomic activity results in hypertension, fever, tachycardia, tachypnea, pupillary dilation, and extensor posturing. ”

“Paroxysmal autonomic instability with dystonia” -PAID is a syndrome attributed to altered autonomic activity.

Clinical manifestations consist of a temperature of 38.5º C, hypertension, a pulse rate of at least 130 beats per minute, a respiratory rate of at least 140 breaths per minute, intermittent agitation, and diaphoresis; these are accompanied by dystonia (rigidity or decerebrate posturing for a duration of at least 1 cycle per d for at least 3 d).

Other issues that can occur because of autonomic dysregulation are electrocardiographic alterations, arrhythmias, increased intracranial pressure (ICP), hypohidrosis, subnormal temperature in flaccid limbs, and neurogenic lung disease.

Damage to these areas releases control of vegetative functions and results in dysregulation of overall autonomic balance
Cortical areas that influence the activity of the hypothalamus include the orbitofrontal, anterior temporal, and insular regions.

Subcortical areas that influence the hypothalamus include the amygdala (particularly the central nucleus), the peri-aqueductal gray, the nucleus of the tractus solitarius, the cerebellar uvula, and the cerebellar vermis.

The pre-optic area of the hypothalamus contains heat-sensitive neurons


Written by M Khairul Z

December 25, 2009 at 6:45 am

Posted in Uncategorized

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