Dengue and Reactive lymphocytes
I found this journal on Internation Medical Journal –
A Descriptive Study of Blood Films of Patients Serologically Positive for Dengue in Hospital Tengku Ampuan Afzan, Kuantan ABSTRACT Introduction: Dengue is one of the commonest infections in Malaysia and it is a notiﬁ able disease. Even though the diagnosis of classical dengue fever and dengue haemorrhagic fever can be recognized clinically, the diagnosis remains a challenge in areas where it could not be differentiated with other febrile illnesses. The aim of this study was to focus on the speciﬁ c and consistent morphological features observed in blood ﬁ lms of dengue infection. Materials and Methods: In all 400 cases of dengue infection serologically diagnosed in the Tengku Ampuan Afzan Hospital (HTAA) during May to October 2007, only a total of 27 cases had blood ﬁ lms examined, and thus were included in this study. These blood ﬁ lms were re-examined by two pathologists from HTAA. The full blood count parameters were also retrieved and studied. Results: We consistently found typical reactive lymphocytes [n= 23 (85%)] and thrombocytopenia [n=21, (77.8%)] in the cases. However, leucopenia was present only in 9 cases (33%). Conclusion: The presence of typical reactive lymphocyte is a consistent ﬁ nding in dengue fever and thus could have a signiﬁ cant role in supporting the diagnosis of dengue infection Interesting hey!