Khairulorama- Life and work notes

Pain is the predecessor of success.

What is the KRas gene?

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KRas genes codes for the GTPase and is an important component in many signal transduction pathway

 

Around 80-90% of pancreatic adenocarcinomas have mutation demonstrated in the KRas 2 gene.

 

Around 50% on pancreatic adenocarcinoma also carry mutation in p53

 

p16 mutations are seen in 30% of chronic pancreatitis

Pancreatic carcinoma is associated with BRCA-2 mutations.

 

Other assocaited ca are breat and a skin condition called icthyosis

 

 

Written by khairulorama

March 21, 2014 at 7:46 am

Posted in Uncategorized

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